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Latest Research Articles From JNNP


    • Anatomical connectivity elucidated by analysing thalamic atrophy in neuromyelitis optica

      The thalamus serves various functions, but it primarily acts as a relay that receives sensory information and sends it to the cerebral cortex. In fact, inputs from the retina are sent to the lateral geniculate nucleus, which projects to the visual cortex in the occipital lobe. Meanwhile, the ventral posterior nucleus (VPN) is a key relay centre of somatosensory information that receives touch and …

     

    • Deep brain stimulation in Tourette syndrome: the known and the unknown

      How much data are needed to conclude the effectiveness of deep brain stimulation in Tourette syndrome? The paper by Johnson et al1 is based on a collaboration with the International Tourette Syndrome (TS) Deep Brain Stimulation (DBS) database and registry. This TS DBS database/registry has been initiated in 2012 by a group of researchers and clinicians led by Michael Okun. They aimed to collect as …

     

     

     

    • Clinical implications of early caudate dysfunction in Parkinsons disease

      Objective Although not typical of Parkinson’s disease (PD), caudate dopaminergic dysfunction can occur in early stages of the disease. However, its frequency and longitudinal implications in large cohorts of recently diagnosed patients remain to be established. We investigated the occurrence of caudate dopaminergic dysfunction in the very early phases of PD (<2 years from diagnosis) using …