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Latest Research Articles From JNNP


    • Suggestibility in functional neurological disorders

      A meta-analysis shows increased suggestibility in patients with functional neurological disorders From the simple message of ‘I will please’ (Latin placēbō) encapsulated in a sugar pill, to the famous theatrics of Jean-Martin Charcot’s hypnotic seizure inductions and treatments (figure 1), implicit and explicit narratives of healing and illness have been noted to exer …

     

    • The stage is set for a new trial end point in ALS

      Al-Chalabi et al report the findings of a post-hoc analysis of edaravone study 19 to explore the performance of two clinical staging systems.1 2 This interesting work is not intended to settle the efficacy debate around edaravone which requires further prospective studies but it does demonstrate that the information provided by the staging systems may compliment current outcome measures. The amyot …

     

     

     

    • Location of intracranial aneurysms is the main factor associated with rupture in the ICAN population

      Background and purpose The ever-growing availability of imaging led to increasing incidentally discovered unruptured intracranial aneurysms (UIAs). We leveraged machine-learning techniques and advanced statistical methods to provide new insights into rupture intracranial aneurysm (RIA) risks. Methods We analysed the characteristics of 2505 patients with intracranial aneurysms (IA) discovered betwe …